The term'd be assigned male at birth, which is different in that in emphasizes the assumption made without stating it to be correct.
Once a clandestine scholar of Vinheim and exiled once he became Undead, Adrian finds himself reawakened by the bell tower as the fire fades.
Given this and the fact that Gwyndolin has visible breasts and whatnot, evidencing estrogen-based puberty unless gods work differently in that regard, I consider him to probably be a trans man.
Obviously some stuff's changed a bit so forgive me.